Required for DNA synthesis and cell division. The synthetic precursor to folate — conversion to the active 5-MTHF form is impaired in around 40% of people due to the MTHFR gene variant.
Why this form
Folic acid (pteroylmonoglutamic acid) is the most stable and well-researched form of vitamin B9, reliably converted to active folate after ingestion and suitable for the majority of the population for everyday supplementation.
Key benefits
DNA synthesis & cell division
Folate is essential for the de novo synthesis of purines and thymidylate, the building blocks of DNA. It is required by every dividing cell, making it especially important for rapidly regenerating tissues.
Red blood cell production
Folate works alongside vitamin B12 to support the normal synthesis of haemoglobin and the maturation of red blood cells, contributing to normal red blood cell formation.
Homocysteine regulation
Folate is the primary methyl donor in the remethylation of homocysteine to methionine, contributing to normal homocysteine metabolism.
Supports